{"id":7793804181729,"title":"Jarrow Formulas SAMe 400 mg - 30 Tablets - Highest Concentration of Active S,S Form - Supports Joint Health, Liver Function, Brain Metabolism, Mood \u0026 Antioxidant Defense - 30 Servings 30 Count (Pack of 1)","handle":"jarrow-formulas-same-400-mg-30-tablets-highest-concentration-of-active-s-s-form-supports-joint-health-liver-function-brain-metabolism-mood-antioxidant-defense-30-servings-30-count-pack-of-1","description":"\u003ch3\u003eJarrow Formulas SAMe 400 mg - 30 Tablets - Highest Concentration of Active S,S Form - Supports Joint Health, Liver Function, Brain Metabolism, Mood \u0026amp; Antioxidant Defense - 30 Servings\u003c\/h3\u003e\n\u003cp id=\"b\"\u003eSAMe is a metabolite of methionine (an essential amino\nacid). The formula provides 400 mg from 800 mg of SAMetosylate disulfate. The\nbiologically active form of SAMe is the S,S structure. This formula is made\nnaturally by fermentation and processed without chemical solvents to preserve\n68-80% S,S SAMe, the highest active level available. SAMe supports the\nproduction of healthy connective tissue. Plus, SAMe metabolism supports the\nsynthesis of glutathione, which is critical for antioxidant defenses and liver\nfunctions. SAMe methylation reactions are involved in the synthesis of\nphosphatidylcholine and neurotransmitters such as dopamine, norepinephrine,\nand serotonin, and has been shown to have a positive effect on mood. The\nformula is manufactured under low temperature and enteric-coated to ensure a\nbiologically active product. Jarrow Formulas SAM-e 400, 400mg, 30\nTabletsAt a Glance:Contributes to the proper functioning of many biochemical\nsystemsIdeal for those wanting to optimize cognitive function, mood, energy\nlevels, liver activity and joint healthPreserved bioavailability through low-\ntemp and low-moisture manufacturingProcessed without solventsProtected from\ndegradation via enteric coating and blister-packaging SAM-e contributes to the\nproper functioning of many biochemical systems. S-adenosyl-L-methionine\n(SAM-e) is an amino acid derivative clinically documented to benefit brain,\nliver and joint function. View larger. S-adenosyl-L-methionine (SAM-e) is an\namino acid derivative clinically documented to benefit brain, liver and joint\nfunction. Found in all living cells, SAM-e is called \"activated methionine\"\nand is formed via combination of ATP with methionine. Somewhat\ncounterintuitively, however, methionine supplementation does not elevate SAM-e\nlevels in the body. Rather, it elevates problematic homocysteine. SAM-e has\nundergone many clinical trials involving thousands of human subjects.\nResearchers have identified many structure- and function-based benefits of\nSAM-e involving over 40 biochemical processes. It is a biochemical workhorse\nwith various diverse effects on the body, including improving liver function,\nsupporting joint health and lifting mood.Liver Detoxification SAM-e\nmetabolism supports glutathione (GSH) synthesis and glutathione-dependent\nenzymes, which support liver function. GSH, the chief antioxidant and\ndetoxifier inside cells, scavenges free radicals produced during carbohydrate\nbreakdown for energy. Taurine is another end product of SAM-e metabolism. GSH\nand taurine are important for liver detoxification.Brain Function SAM-e\nsupports brain function by its methylation effects. Methylation is the\ntransfer of a methyl group (one carbon and three hydrogen atoms, CH3) from one\nmolecule to another. SAM-e is the most important of all methyl-donors in\nmammalian metabolism. Donation of methyl groups supports numerous metabolic\nprocesses including brain function, energy production and DNA metabolism.\nNeurotransmitters, substances involved in nerve cell communication, are also\nproducts of methylation. These compounds include L-DOPA, dopamine, serotonin,\nepinephrine and phosphatidylcholine (in lecithin). SAM-e is thought to benefit\ncognitive health by supporting the production of such critical brain\nmessengers. In fact, many people report noticeable positive effects on brain\nand mood after only taking it for a short time.Energy Production Methylation\nfrom SAM-e is also critical for creatine production. Creatine metabolites are\nimportant for ADP to ATP recycling and storing energy for immediate needs.\nSupporting creatine levels may help maximize physical performance, reduce\nexercise fatigue and improve recovery after exercise.Longevity A healthy\nyoung body manufactures all the SAM-e it needs. However, with age, people are\nless able to produce adequate SAM-e. This may contribute to declining health\non many levels. Fortunately, these disturbances are often boosted by SAM-e\nsupplementation. In addition, methylation of DNA is an important part of DNA\nrepair. De-methylation of DNA contributes to the aging process. Proper\nmethylation, via substances such as SAM-e, positively influences\nlongevity.Healthy Connective Tissue Research has shown that regular SAM-e\nsupplementation helps support joint health, and is used regularly in Europe to\npromote joint mobility and comfort.Not All SAM-e is Created Equal SAM-e\nexists in two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form\nis the (S,S) structure, while the (R,S) structure is inactive. Jarrow Formulas\nSAM-e is predominantly the active form. It is made naturally by\nmicrobiological fermentation and then specially processed, without solvents,\nto preserve 68-80 percent (S,S) SAM-e, the highest active level available.\nSAM-e is a highly reactive molecule and very fragile. It degrades rapidly\nunder high heat or humidity. Improper handling of SAM-e can cause degradation\nin a matter of hours. Thus, the manufacturing process for Jarrow Formulas\nSAM-e is done under low temperature and low humidity, and the tablet is\nenteric coated and blister-packed. Pharmacokinetic studies show that oral\nsupplementation of SAM-e is most effective when enteric-coated by special\ngastric fluid-resistant polymers, resulting in maximum blood levels.Note:\nSide effects are rare and appear to be limited to gastrointestinal\ndisturbances. This product complies with the proposed USP Monograph for\nSAM-e.Warning: Individuals using prescribed medications such as\nantidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs)\nand MAO Inhibitors should consult a physician before using. Individuals with\nParkinson's disease, bi-polar disorder or manic depression should not use\nSAM-e.About Jarrow Formulas Jarrow Formulas' complete line of over 350\nnutritional products includes vitamins, minerals, probiotics, standardized\nherbal concentrates, amino acids, enzymes and enteral nutrition products.\nCustomers can be assured of purity, value and potency when choosing these\nproducts.What's in the Box Jarrow Formulas SAM-e 400, 400mg, 30 Tablets.Other\nProducts from Jarrow Formulas\u003c\/p\u003e \n\n\u003ch3\u003eProduct Features\u003c\/h3\u003e\n \u003cul class=\"a\"\u003e\n \u003cli\u003eHighest Concentration of Active S,S Form: The biologically active form of SAMe is the S,S structure; The formula is made by fermentation and processed without chemical solvents to preserve 68-80 percent S,S SAMe, the highest active level available\u003c\/li\u003e\n \u003cli\u003eJoint Health, Liver Function and Antioxidant Defense: SAMe supports the production of healthy connective tissue; Plus, SAMe metabolism supports the synthesis of glutathione, which is critical for antioxidant defenses and liver functions\u003c\/li\u003e\n \u003cli\u003eBrain Metabolism and Mood: SAMe methylation reactions are involved in the synthesis of phosphatidylcholine and neurotransmitters such as dopamine, norepinephrine, and serotonin; The formula has been shown to have a positive effect on mood\u003c\/li\u003e\n \u003cli\u003eEnteric Coating: SAMe is a metabolite of methionine (an essential amino acid); This formula provides 400 mg from 800 mg of SAMetosylate disulfate and is manufactured under low temperature and enteric-coated to ensure a biologically active product\u003c\/li\u003e\n \u003cli\u003eSuperior Nutrition and Formulation: The goal of Jarrow Formulas is to promote optimal health with high-quality, effective, affordable, and superior formulation of dietary supplements; Our customers can be assured of purity, value, and potency\u003c\/li\u003e\n \u003c\/ul\u003e\n\u003chr class=\"py-vbody\" style=\"display: none\"\u003e\n\n\n","published_at":"2025-02-18T18:17:01+11:00","created_at":"2022-08-17T20:05:24+10:00","vendor":"Jarrow Formulas","type":"Multi-Enzymes","tags":["health_2022","hidden"],"price":16200,"price_min":16200,"price_max":16200,"available":true,"price_varies":false,"compare_at_price":null,"compare_at_price_min":0,"compare_at_price_max":0,"compare_at_price_varies":false,"variants":[{"id":43156988494049,"title":"Default Title","option1":"Default Title","option2":null,"option3":null,"sku":"B0013OSJU0","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Jarrow Formulas SAMe 400 mg - 30 Tablets - Highest Concentration of Active S,S Form - Supports Joint Health, Liver Function, Brain Metabolism, Mood \u0026 Antioxidant Defense - 30 Servings 30 Count (Pack of 1)","public_title":null,"options":["Default Title"],"price":16200,"weight":59,"compare_at_price":null,"inventory_management":null,"barcode":"790011200208","requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}],"images":["\/\/outfitocean.com\/cdn\/shop\/products\/B0013OSJU0.jpg?v=1669848251","\/\/outfitocean.com\/cdn\/shop\/products\/71qqnJ-mWiS.jpg?v=1660730724","\/\/outfitocean.com\/cdn\/shop\/products\/81k1I0s0nGS.jpg?v=1660730724","\/\/outfitocean.com\/cdn\/shop\/products\/712J16O-EpS_b297d15f-5ec8-4e00-820e-d39b298f3a2b.jpg?v=1660730725","\/\/outfitocean.com\/cdn\/shop\/products\/71IuWvA_ysS_b4a461ea-dcdf-43ef-998e-c9f8b45a50a5.jpg?v=1660730725","\/\/outfitocean.com\/cdn\/shop\/products\/81TzsgL2iOL_23646e44-cfbb-433a-9f1c-e062aeaa6813.jpg?v=1660730725","\/\/outfitocean.com\/cdn\/shop\/products\/81YRELG-M_L_67ce5b70-b335-4849-8770-3db81c40036e.jpg?v=1660730725"],"featured_image":"\/\/outfitocean.com\/cdn\/shop\/products\/B0013OSJU0.jpg?v=1669848251","options":["Title"],"media":[{"alt":"[Australia] - 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Jarrow Formulas SAMe 400 mg - 30 Tablets - Highest Concentration of Active S,S Form - Supports Joint Health, Liver Function, Brain Metabolism, Mood \u0026 Antioxidant Defense - 30 Servings 30 Count (Pack of 1) ","id":30550632268001,"position":7,"preview_image":{"aspect_ratio":1.0,"height":2000,"width":2000,"src":"\/\/outfitocean.com\/cdn\/shop\/products\/81YRELG-M_L_67ce5b70-b335-4849-8770-3db81c40036e.jpg?v=1660730725"},"aspect_ratio":1.0,"height":2000,"media_type":"image","src":"\/\/outfitocean.com\/cdn\/shop\/products\/81YRELG-M_L_67ce5b70-b335-4849-8770-3db81c40036e.jpg?v=1660730725","width":2000}],"requires_selling_plan":false,"selling_plan_groups":[],"content":"\u003ch3\u003eJarrow Formulas SAMe 400 mg - 30 Tablets - Highest Concentration of Active S,S Form - Supports Joint Health, Liver Function, Brain Metabolism, Mood \u0026amp; Antioxidant Defense - 30 Servings\u003c\/h3\u003e\n\u003cp id=\"b\"\u003eSAMe is a metabolite of methionine (an essential amino\nacid). The formula provides 400 mg from 800 mg of SAMetosylate disulfate. The\nbiologically active form of SAMe is the S,S structure. This formula is made\nnaturally by fermentation and processed without chemical solvents to preserve\n68-80% S,S SAMe, the highest active level available. SAMe supports the\nproduction of healthy connective tissue. Plus, SAMe metabolism supports the\nsynthesis of glutathione, which is critical for antioxidant defenses and liver\nfunctions. SAMe methylation reactions are involved in the synthesis of\nphosphatidylcholine and neurotransmitters such as dopamine, norepinephrine,\nand serotonin, and has been shown to have a positive effect on mood. The\nformula is manufactured under low temperature and enteric-coated to ensure a\nbiologically active product. Jarrow Formulas SAM-e 400, 400mg, 30\nTabletsAt a Glance:Contributes to the proper functioning of many biochemical\nsystemsIdeal for those wanting to optimize cognitive function, mood, energy\nlevels, liver activity and joint healthPreserved bioavailability through low-\ntemp and low-moisture manufacturingProcessed without solventsProtected from\ndegradation via enteric coating and blister-packaging SAM-e contributes to the\nproper functioning of many biochemical systems. S-adenosyl-L-methionine\n(SAM-e) is an amino acid derivative clinically documented to benefit brain,\nliver and joint function. View larger. S-adenosyl-L-methionine (SAM-e) is an\namino acid derivative clinically documented to benefit brain, liver and joint\nfunction. Found in all living cells, SAM-e is called \"activated methionine\"\nand is formed via combination of ATP with methionine. Somewhat\ncounterintuitively, however, methionine supplementation does not elevate SAM-e\nlevels in the body. Rather, it elevates problematic homocysteine. SAM-e has\nundergone many clinical trials involving thousands of human subjects.\nResearchers have identified many structure- and function-based benefits of\nSAM-e involving over 40 biochemical processes. It is a biochemical workhorse\nwith various diverse effects on the body, including improving liver function,\nsupporting joint health and lifting mood.Liver Detoxification SAM-e\nmetabolism supports glutathione (GSH) synthesis and glutathione-dependent\nenzymes, which support liver function. GSH, the chief antioxidant and\ndetoxifier inside cells, scavenges free radicals produced during carbohydrate\nbreakdown for energy. Taurine is another end product of SAM-e metabolism. GSH\nand taurine are important for liver detoxification.Brain Function SAM-e\nsupports brain function by its methylation effects. Methylation is the\ntransfer of a methyl group (one carbon and three hydrogen atoms, CH3) from one\nmolecule to another. SAM-e is the most important of all methyl-donors in\nmammalian metabolism. Donation of methyl groups supports numerous metabolic\nprocesses including brain function, energy production and DNA metabolism.\nNeurotransmitters, substances involved in nerve cell communication, are also\nproducts of methylation. These compounds include L-DOPA, dopamine, serotonin,\nepinephrine and phosphatidylcholine (in lecithin). SAM-e is thought to benefit\ncognitive health by supporting the production of such critical brain\nmessengers. In fact, many people report noticeable positive effects on brain\nand mood after only taking it for a short time.Energy Production Methylation\nfrom SAM-e is also critical for creatine production. Creatine metabolites are\nimportant for ADP to ATP recycling and storing energy for immediate needs.\nSupporting creatine levels may help maximize physical performance, reduce\nexercise fatigue and improve recovery after exercise.Longevity A healthy\nyoung body manufactures all the SAM-e it needs. However, with age, people are\nless able to produce adequate SAM-e. This may contribute to declining health\non many levels. Fortunately, these disturbances are often boosted by SAM-e\nsupplementation. In addition, methylation of DNA is an important part of DNA\nrepair. De-methylation of DNA contributes to the aging process. Proper\nmethylation, via substances such as SAM-e, positively influences\nlongevity.Healthy Connective Tissue Research has shown that regular SAM-e\nsupplementation helps support joint health, and is used regularly in Europe to\npromote joint mobility and comfort.Not All SAM-e is Created Equal SAM-e\nexists in two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form\nis the (S,S) structure, while the (R,S) structure is inactive. Jarrow Formulas\nSAM-e is predominantly the active form. It is made naturally by\nmicrobiological fermentation and then specially processed, without solvents,\nto preserve 68-80 percent (S,S) SAM-e, the highest active level available.\nSAM-e is a highly reactive molecule and very fragile. It degrades rapidly\nunder high heat or humidity. Improper handling of SAM-e can cause degradation\nin a matter of hours. Thus, the manufacturing process for Jarrow Formulas\nSAM-e is done under low temperature and low humidity, and the tablet is\nenteric coated and blister-packed. Pharmacokinetic studies show that oral\nsupplementation of SAM-e is most effective when enteric-coated by special\ngastric fluid-resistant polymers, resulting in maximum blood levels.Note:\nSide effects are rare and appear to be limited to gastrointestinal\ndisturbances. This product complies with the proposed USP Monograph for\nSAM-e.Warning: Individuals using prescribed medications such as\nantidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs)\nand MAO Inhibitors should consult a physician before using. Individuals with\nParkinson's disease, bi-polar disorder or manic depression should not use\nSAM-e.About Jarrow Formulas Jarrow Formulas' complete line of over 350\nnutritional products includes vitamins, minerals, probiotics, standardized\nherbal concentrates, amino acids, enzymes and enteral nutrition products.\nCustomers can be assured of purity, value and potency when choosing these\nproducts.What's in the Box Jarrow Formulas SAM-e 400, 400mg, 30 Tablets.Other\nProducts from Jarrow Formulas\u003c\/p\u003e \n\n\u003ch3\u003eProduct Features\u003c\/h3\u003e\n \u003cul class=\"a\"\u003e\n \u003cli\u003eHighest Concentration of Active S,S Form: The biologically active form of SAMe is the S,S structure; The formula is made by fermentation and processed without chemical solvents to preserve 68-80 percent S,S SAMe, the highest active level available\u003c\/li\u003e\n \u003cli\u003eJoint Health, Liver Function and Antioxidant Defense: SAMe supports the production of healthy connective tissue; Plus, SAMe metabolism supports the synthesis of glutathione, which is critical for antioxidant defenses and liver functions\u003c\/li\u003e\n \u003cli\u003eBrain Metabolism and Mood: SAMe methylation reactions are involved in the synthesis of phosphatidylcholine and neurotransmitters such as dopamine, norepinephrine, and serotonin; The formula has been shown to have a positive effect on mood\u003c\/li\u003e\n \u003cli\u003eEnteric Coating: SAMe is a metabolite of methionine (an essential amino acid); This formula provides 400 mg from 800 mg of SAMetosylate disulfate and is manufactured under low temperature and enteric-coated to ensure a biologically active product\u003c\/li\u003e\n \u003cli\u003eSuperior Nutrition and Formulation: The goal of Jarrow Formulas is to promote optimal health with high-quality, effective, affordable, and superior formulation of dietary supplements; Our customers can be assured of purity, value, and potency\u003c\/li\u003e\n \u003c\/ul\u003e\n\u003chr class=\"py-vbody\" style=\"display: none\"\u003e\n\n\n"}