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Methylation (donation of methyl groups)\nis an essential process in ensuring the proper function of a number of organ\nsystems. SAMe is involved in numerous biochemical reactions in tissue\nincluding the liver, joints and brain. SAMe is also required for the\nbiosynthesis of critical neurotransmitters and hormones. The manufacturing\nprocess of SAMe yields two forms, the S,S and the R,S isomers. The S,S isomer\nis the active form that mediates biochemical activity in the human body,\nwhereas the R,S form is considered to be biologically inactive. The Italian\nSAMe used in Double-Strength SAMe 400 is processed to yield the highest\navailable percentage of the active pure S,S form on the market. SAMe may\nenhance cartilage protection and promote the synthesis of proteoglycans,\nessential components of connective tissue. Clinical studies show an ability of\nSAMe to enhance mobility and movement, and promote joint comfort. SAMe-\ncatalyzed methylation reactions promote the synthesis of neurotransmitters,\nwhich have the potential to promote enhanced mood. SAMe may also upregulate\nthe production of phosphatidylcholine, supporting cognitive function. SAMe\nenhances liver synthesis of glutathione, an antioxidant. Glutathione promotes\ndetoxification and liver protection. 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Doctor's Best utilizes\nonly the highest quality Italian SAMe available on the market. This ensures\nthat you receive the most potent SAMe product with the highest percentage of\nthe active S,S form per serving, bar none. S-Adenosyl Methionine (SAMe) is\nderived from the amino acid methionine and is one of the most important methyl\ndonors in the central nervous system. Methylation (donation of methyl groups)\nis an essential process in ensuring the proper function of a number of organ\nsystems. SAMe is involved in numerous biochemical reactions in tissue\nincluding the liver, joints and brain. SAMe is also required for the\nbiosynthesis of critical neurotransmitters and hormones. The manufacturing\nprocess of SAMe yields two forms, the S,S and the R,S isomers. The S,S isomer\nis the active form that mediates biochemical activity in the human body,\nwhereas the R,S form is considered to be biologically inactive. The Italian\nSAMe used in Double-Strength SAMe 400 is processed to yield the highest\navailable percentage of the active pure S,S form on the market. SAMe may\nenhance cartilage protection and promote the synthesis of proteoglycans,\nessential components of connective tissue. Clinical studies show an ability of\nSAMe to enhance mobility and movement, and promote joint comfort. SAMe-\ncatalyzed methylation reactions promote the synthesis of neurotransmitters,\nwhich have the potential to promote enhanced mood. SAMe may also upregulate\nthe production of phosphatidylcholine, supporting cognitive function. SAMe\nenhances liver synthesis of glutathione, an antioxidant. Glutathione promotes\ndetoxification and liver protection. Studies show SAMe may protect liver\ntissue from injury caused by a number of toxins.\u003c\/p\u003e \n\n\u003ch3\u003eProduct Features\u003c\/h3\u003e\n \u003cul class=\"a\"\u003e\n \u003cli\u003eDoctor's Best SAMe Double Strength is proven to enhance mood and promote cognitive health\u003c\/li\u003e\n \u003cli\u003eSAMe is essential for the healthy metabolism of the major brain transmitters dopamine, serotonin and norepinephrine\u003c\/li\u003e\n \u003cli\u003eSAMe has been proven to promote joint comfort and mobility and supports liver health and detoxification\u003c\/li\u003e\n \u003cli\u003eSAMe's effectiveness has been proven with 18 controlled human trials published over 40 years\u003c\/li\u003e\n \u003cli\u003ePharmaceutical grade, Non-GMO, Gluten Free, Vegan\u003c\/li\u003e\n \u003c\/ul\u003e\n\u003chr class=\"py-vbody\" style=\"display: none\"\u003e\n\n\n"}

Doctor's Best SAM-e 400 mg, Vegan, Gluten Free, Soy Free, Mood and Joint Support, 60 Enteric Coated Tablets 60 Count (Pack of 1)

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Doctor's Best SAM-e 400 mg, Vegan, Gluten Free, Soy Free, Mood and Joint Support, 60 Enteric Coated Tablets

SAMe 400 contains 400 mg of active SAMe in each tablet. Doctor's Best utilizes only the highest quality Italian SAMe available on the market. This ensures that you receive the most potent SAMe product with the highest percentage of the active S,S form per serving, bar none. S-Adenosyl Methionine (SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissue including the liver, joints and brain. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones. The manufacturing process of SAMe yields two forms, the S,S and the R,S isomers. The S,S isomer is the active form that mediates biochemical activity in the human body, whereas the R,S form is considered to be biologically inactive. The Italian SAMe used in Double-Strength SAMe 400 is processed to yield the highest available percentage of the active pure S,S form on the market. SAMe may enhance cartilage protection and promote the synthesis of proteoglycans, essential components of connective tissue. Clinical studies show an ability of SAMe to enhance mobility and movement, and promote joint comfort. SAMe- catalyzed methylation reactions promote the synthesis of neurotransmitters, which have the potential to promote enhanced mood. SAMe may also upregulate the production of phosphatidylcholine, supporting cognitive function. SAMe enhances liver synthesis of glutathione, an antioxidant. Glutathione promotes detoxification and liver protection. Studies show SAMe may protect liver tissue from injury caused by a number of toxins.

Product Features

  • Doctor's Best SAMe Double Strength is proven to enhance mood and promote cognitive health
  • SAMe is essential for the healthy metabolism of the major brain transmitters dopamine, serotonin and norepinephrine
  • SAMe has been proven to promote joint comfort and mobility and supports liver health and detoxification
  • SAMe's effectiveness has been proven with 18 controlled human trials published over 40 years
  • Pharmaceutical grade, Non-GMO, Gluten Free, Vegan

Buy with confidence as this product comes with 18 months full local warranty in Australia & New Zealand (unless otherwise stated in the overview).

This product also comes with the benefits of the CocoonPower Warranty. For further details please read our Warranty Guidelines.

You can also purchase 3 Year Extended Care. If you are interested please see our Extended Care Information.